Executive Leadership & Medical Team

The American Center for Organ Restoration is led by a team of professionals who helped advance the fields of transplantation, cellular therapeutics, and immune-based medicine. Their combined expertise forms the foundation of our Center’s scientific and medical excellence.

Each member brings decades of experience in the management of complex organ, metabolic, inflammatory, and immunologic disorders. Together, they share one mission: to deliver next-generation therapies that address the root causes of organ dysfunction and support restoration wherever biologically possible.

Gregory DiRienzo, CEO/Founder

Chief Executive Officer

Founder/CEO of ICCA Global Cancer Center (www.treatyourcancer.com). Founder/CEO of ProGenaCell Regenerative Medicine (www.progenacell.com) an international regenerative healthcare provider with affiliate cell therapy clinics in Westhausen and Koln, Germany respectively; former trustee of the Graduate School of Biological Sciences, Western University of Health Sciences, and former CEO of PDA Solutions, an innovative medical software company.

Greg DiRienzo
Leonard Makowka

Leonard Makowka, MD, PhD, Founder

Chief Scientific Officer, Surgical and Cellular Therapeutics

Dr. Leonard Makowka is internationally recognized as one of the most influential figures in modern organ transplantation and hepatobiliary surgery. His career spans more than four decades of groundbreaking work in liver transplantation, complex hepatobiliary procedures, and advanced cellular medicine.

Highlights:

  •   Served as Chief of Surgery at Cedars-Sinai Medical Center.
  •   Led one of the highest-volume liver transplantation programs globally.
  •   Published an extensive body of scientific literature across surgery, immunology, and transplantation.
  •   Mentored and trained hundreds of surgeons worldwide.
  •   Developed and proctored advanced organ-based therapeutic techniques that are used today across multiple countries.

Dr. Makowka’s curriculum vitae is a reflection of a lifetime of contributions to the surgical field and translational research. His leadership provides the Center with extraordinary clinical expertise and global credibility. Patients benefit from the guidance of a physician who helped define many of the modern standards in liver and organ care.

Kenneth Yaker, MD, Founder

Director, Functional and Immune-Regenerative Medicine

Dr. Kenneth Yaker is a distinguished clinician in integrative and functional medicine. His expertise focuses on the identification and correction of the biochemical, metabolic, and immunologic imbalances that contribute to chronic inflammation and organ dysfunction.

His expertise includes:

  •   Extensive experience in the management of complex chronic conditions with immune, metabolic, and cellular therapeutics.
  •   Deep knowledge of functional diagnostics and inflammatory biomarkers.
  •   Design of patient-specific treatment plans based on molecular and cellular physiology.
  •   Integration of advanced cellular modalities into long-term Regenerative care.
Leonard Makowka

Dr. Yaker provides patients with a comprehensive plan that evaluates their global physiology rather than isolated symptoms.

Hebert Schramm

Hebert Schramm, MD, Founder

Chief Medical Officer, Functional and Immune-Regenerative Medicine

Dr. Schramm brings extensive expertise in diagnostics, surgical, oncologic, integrative, metabolic, and inflammation-focused medicine. His approach combines conventional diagnostics with advanced cellular and molecular therapeutics.

His work includes:

  •   Development of clinically integrated approaches that target inflammatory, metabolic, and immune drivers of organ dysfunction.
  •   Collaboration on next-generation regenerative protocols.
  •   Years of experience in the evaluation and treatment of complex multi-system conditions.
  •   Emphasis on precision diagnostics and personalized therapeutic mapping.

Scientific Advisors and Collaborators

Our medical team also collaborates with leading scientists, laboratory directors, and cellular therapy innovators across the world.

Our network includes experts in:

  •   Induced pluripotent stem cell (iPSC) technology.
  •   Hepatocyte-like cell development.
  •   Cellular immunotherapy.
  •   NK cell engineering.
  •   Advanced biological manufacturing.
  •   Regenerative organ medicine.

These collaborations strengthen our scientific capabilities and ensure that our protocols remain aligned with the most current global advancements.

Clinical Philosophy

Our leadership team shares a unified philosophy:

  1. Treat the underlying mechanisms of disease.
    Organ dysfunction rarely begins in the organ. It begins at the cellular and immunologic levels. Our protocols target inflammation, fibrosis, immune imbalance, and cellular loss.
  2. Use advanced technology responsibly.
    Every therapy ACOR provides is selected based on biological rationale, clinical insight, and rigorous safety considerations.
  3. Personalize every decision.
    No protocol is generalized. Every patient receives a plan that’s built around their individual diagnostics, biomarkers, immune patterns, and disease trajectory.
  4. Integrate experience with innovation.
    Our team takes advantage of decades of clinical practice and the potential of next-generation cellular and immunologic science.

A Team Committed to Excellence

The American Center for Organ Restoration exists because of the vision, dedication, and scientific leadership of physicians who have devoted their careers to redefining what is possible in organ Regenerative medicine.

Their experience ensures that every patient receives:

  •   Accurate medical evaluation.
  •   Honest and evidence-based recommendations.
  •   Expert integration of cellular and Regenerative therapies.
  •   A comprehensive, personalized, and medically responsible treatment plan.

Restoring Hope. Restoring Life!

Give us a call today to see what our team can do for you and your loved ones.